dog Epididymal secretory protein E1 Antibody from MYBIOSOURCE INC.

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Antigenic Specificitydog Epididymal secretory protein E1
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesdog
Isotypen/a
Formatbiotin conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionIntracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment. Both NPC1 and NPC2 function as the cellular 'tag team duo' (TTD) to catalyze the mobilization of cholesterol within the multivesicular environment of the late endosome (LE) to effect egress through the limiting bilayer of the LE. NPC2 binds unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes and transfers it to the cholesterol-binding pocket of the N-terminal domain of NPC1. Cholesterol binds to NPC1 with the hydroxyl group buried in the binding pocket and is exported from the limiting membrane of late endosomes/ lysosomes t
ImmunogenImmunogen: Recombinant dog Epididymal secretory protein E1 protein(22-149aa)
Other Names[Niemann Pick type C2 protein homolog; cE1; NPC2], [NPC2; NPC2; CE1]
Gene, Accession #Gene ID: 403920, NCBI: Q28895.1, UniProt: Q28895
Catalog #MBS1492425
Price$160, $235
Order / More Infodog Epididymal secretory protein E1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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