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Antigenic Specificity | CRTAM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 2.6 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CRTAM protein. The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human cytotoxic and regulatory T cell molecule |
Other Names | [CD355] |
Gene, Accession # | [CRTAM], Gene ID: 56253, NCBI: NP_001291711.1, UniProt: O95727 |
Catalog # | MBS9402291 |
Price | $255 |
Order / More Info | CRTAM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |