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Antigenic Specificity | Phospho-OSR1 (Thr185) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-OSR1 (Thr185) antibody detects endogenous levels of OSR1 only when phosphorylated at Thr185. Function: Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.Subunit Structure: Binds to and phosphorylates PAK1. Interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT.Similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-OSR1 (Thr185) Tissue Specificity: Ubiquitously expressed in all tissue examined. |
Other Names | [2210022N24Rik; 2810422B09Rik; AI462649; AW209236; KIAA1101; mKIAA1101; OSR 1; OSR1; OTTHUMP00000209062; Oxidative stress responsive 1; Oxidative stress responsive 1 protein; Oxidative stress-responsive 1 protein; OXSR 1; OXSR1; OXSR1_HUMAN; Serine/threonine protein kinase OSR1; Serine/threonine-protein kinase OSR1] |
Gene, Accession # | [OSR1], Gene ID: 9943, NCBI: NP_005100.1, UniProt: O95747 |
Catalog # | MBS9609059 |
Price | $240, $280 |
Order / More Info | Phospho-OSR1 (Thr185) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |