ATF4 (Phospho-Ser245) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityATF4 (Phospho-Ser245)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsImmunoblotting (IB), Immunohistochemistry (IHC)
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DescriptionThis antibody detects endogenous human ATF4 only when phosphorylated at serine 245. ATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA-binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. ATF4 belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Diseases associated with ATF4 include leukoencephalopathy with vanishing white matter and T-cell le
ImmunogenAntigen: Peptide sequence that includes phosphorylation sites of serine 245 (N-R-S(p)-L-P) derived from human ATF4 and conjugated to KLH.
Other Names[cyclic AMP-dependent transcription factor ATF-4; Cyclic AMP-dependent transcription factor ATF-4; cyclic AMP-dependent transcription factor ATF-4; activating transcription factor 4; Activating transcription factor 4; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67; Tax-responsive enhancer element-binding protein 67; TaxREB67], [ATF4; ATF4; CREB2; TXREB; CREB-2; TAXREB67; CREB2; TXREB; cAMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; TaxREB67]
Gene, Accession #[ATF4], Gene ID: 468, NCBI: NP_001666.2, UniProt: P18848
Catalog #MBS191065
Price$340
Order / More InfoATF4 (Phospho-Ser245) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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