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Antigenic Specificity | Trk A (Phospho Tyr680/Y681) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Trk A (Y680/Y681) Polyclonal Antibody detects endogenous levels of Trk A protein only when phosphorylated at Y680/Y681. NTRK1 encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
Immunogen | Immunogen: Synthesized peptide derived from human Trk A around the phosphorylation site of Y680/Y681 |
Other Names | [Rabbit Trk A (phospho Tyr680/Y681); NTRK1; MTC; TRK; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A] |
Gene, Accession # | [TRKA], Gene ID: 4914, NCBI: NP_001007793.1, UniProt: P04629 |
Catalog # | MBS9706054 |
Price | $130, $220, $325 |
Order / More Info | Trk A (Phospho Tyr680/Y681) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |