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Antigenic Specificity | PTP4A1/PRL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PTP4A1/PRL1 antibody detects endogenous levels of PTP4A1/PRL1. Function: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.Subunit Structure: Homotrimer. Interacts with ATF5 (By similarity). Interacts with tubulin.Post-translational Modifications: Farnesylated. Farnesylation is required for membrane targeting. Unfarnesylated forms are shifted into the nucleus.Similarity: Belongs to the protein-tyrosine phosphatase family. |
Immunogen | Immunogen: A synthesized peptide derived from human PTP4A1/PRL1. Subcellular Location: Cell Membrane. Early Endosome. Endoplasmic Reticulum. Cytoplasm. Cytoplasm > Cytoskeleton > Spindle. And mitotic spindle. Tissue Specificity: Expressed in bone marrow, lymph nodes, T lymphocytes, spleen, thymus and tonsil. Overexpressed in tumor cell lines. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Z |
Other Names | [HH 72; HH72; Hypothetical protein DKFZp779M0721; Phosphatase of regenerating liver 1; PRL 1; PRL-1; PRL1; Protein tyrosine phosphatase PTPCAAX1; Protein tyrosine phosphatase type IVA 1; Protein tyrosine phosphatase type IVA member 1; Protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1; Protein-tyrosine phosphatase, type 4A, 1; PTP(CAAXI); Ptp4a1; PTPCAAX1; TP4A1_HUMAN] |
Gene, Accession # | [PTP4A1], Gene ID: 7803, NCBI: NP_003454.1, UniProt: Q93096 |
Catalog # | MBS9603686 |
Price | $240, $280 |
Order / More Info | PTP4A1/PRL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |