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Antigenic Specificity | TNFRSF10C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of human spleen cell lysate using TNFRSF10C antibody. The tumor necrosis factor receptor family, which includes TNF-RI, Fas, DR3, DR4, DR5, and DR6, plays an important role in the regulation of apoptosis in various physiological systems (1, 2). The receptors are activated by a family of cytokines that include TNF, FasL, and TRAIL. They are characterized by a highly conserved extracellular region containing cysteine-rich repeats and a conserved intracellular region of about 80 amino acids termed the death domain (DD). The DD is important for transducing the death signal by recruiting other DD containing adaptor proteins (FADD, TRADD, RIP) to the death-inducing signaling complex (DISC), resulting in activati |
Immunogen | Immunogen: Recombinant protein of human TNFRSF10C |
Other Names | [tumor necrosis factor receptor superfamily member 10C; Tumor necrosis factor receptor superfamily member 10C; tumor necrosis factor receptor superfamily member 10C; TNF receptor superfamily member 10c; Antagonist decoy receptor for TRAIL/Apo-2L; Decoy TRAIL receptor without death domain; Decoy receptor 1; DcR1; Lymphocyte inhibitor of TRAIL; TNF-related apoptosis-inducing ligand receptor 3; TRAIL receptor 3; TRAIL-R3; TRAIL receptor without an intracellular domain; CD_antigen: CD263], [TNFRSF10C; TNFRSF10C; LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR; DCR1; LIT; TRAILR3; TRID; DcR1; TRAIL receptor 3; TRAIL-R3] |
Gene, Accession # | [TNFRSF10C], Gene ID: 8794, NCBI: NP_003832.2, UniProt: O14798 |
Catalog # | MBS419553 |
Price | $385 |
Order / More Info | TNFRSF10C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |