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Antigenic Specificity | Phospho-JMJD2B (S566) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.35 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This JMJD2B Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S566 of human JMJD2B. Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. |
Immunogen | n/a |
Other Names | [Lysine-specific demethylase 4B; 11411-; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B; KDM4B; JHDM3B; JMJD2B; KIAA0876] |
Gene, Accession # | [KDM4B], Gene ID: 23030, NCBI: NP_055830.1, UniProt: O94953 |
Catalog # | MBS9211128 |
Price | $165, $370 |
Order / More Info | Phospho-JMJD2B (S566) Antibody from MYBIOSOURCE INC. |
Product Specific References | Yang, J., et al. Cancer Res. 70(16):6456-6466(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Beyer, S., et al. J. Biol. Chem. 283(52):36542-36552(2008) Pollard, P.J., et al. Biochem. J. 416(3):387-394(2008) Katoh, Y., et al. Int. J. Mol. Med. 20(2):269-273(2007) |