ECSIT Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | ECSIT |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | ion exchange purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Activation of NF-kB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses. Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6. ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possibility of cross-talk |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT. |
| Other Names | [evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform 1; Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; ECSIT signalling integrator; Protein SITPEC] |
| Gene, Accession # | [ECSIT], Gene ID: 51295, NCBI: NP_057665 |
| Catalog # | MBS9403830 |
| Price | $320 |
| Order / More Info | ECSIT Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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