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Antigenic Specificity | TBP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence TATA box. This DNA sequence is found about 25-30 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA |
Immunogen | Immunogen: Fusion protein of human TBP Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [TBP; GTF2D; GTF2D1; MGC117320; MGC126054; MGC126055; SCA17; TFIID] |
Gene, Accession # | [TBP], Gene ID: 6908, NCBI: NP_001165556.1, UniProt: P20226 |
Catalog # | MBS8500994 |
Price | $310 |
Order / More Info | TBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |