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Antigenic Specificity | ELL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ELL protein. Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.Thirman M.J., Proc. Natl. Acad. Sci. U.S.A. 91:12110-12114(1994).Simone F., Blood 98:201-209(2001).Kong S.E., Proc. Natl. Acad. Sci. U.S.A. 102:10094-10098(2005). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human ELL. |
Other Names | [RNA polymerase II elongation factor ELL; RNA polymerase II elongation factor ELL; ELL; C19orf17] |
Gene, Accession # | [ELL], Gene ID: 8178, NCBI: NP_006523.1, UniProt: P55199 |
Catalog # | MBS9407231 |
Price | $200, $255 |
Order / More Info | ELL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |