IREB2 (Center), 201-230 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | IREB2 (Center), 201-230 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, porcine, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This IREB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human IREB2. IREB2 is a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. |
| Immunogen | n/a |
| Other Names | [Iron-responsive element-binding protein 2; IRE-BP 2; Iron regulatory protein 2; IRP2; IREB2] |
| Gene, Accession # | [IREB2], Gene ID: 3658, NCBI: NP_004127.1, UniProt: P48200 |
| Catalog # | MBS9213792 |
| Price | $165, $370 |
| Order / More Info | IREB2 (Center), 201-230 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010) Hansen, H.M., et al. Hum. Mol. Genet. 19(18):3652-3661(2010) Cho, M.H., et al. Nat. Genet. 42(3):200-202(2010) Salahudeen, A.A., et al. Science 326(5953):722-726(2009) DeMeo, D.L., et al. Am. J. Hum. Genet. 85(4):493-502(2009) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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