Human CD45RA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD45RA
Clone[HI100]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b
Formatunconjugated
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunohistochemistry (IHC)
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DescriptionCD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
Immunogenn/a
Other Names[Human CD45RA; Receptor-type tyrosine-protein phosphatase C; Ptprc; L-CA; Ly-5; T200; CD45]
Gene, Accession #[CD45RA], Gene ID: 5788, NCBI: NP_002829.3, UniProt: P08575
Catalog #MBS2553833
Price$60, $100
Order / More InfoHuman CD45RA Antibody from MYBIOSOURCE INC.
Product Specific References1. Thomas M. 1989. Annu. Rev. Immunol. 7:339. 2. Trowbridge I, et al. 1994. Annu. Rev. Immunol.12:85.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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