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Antigenic Specificity | NEU1 (Center), 188-214 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This NEU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-214 amino acids from the Central region of human NEU1. The protein encoded by this gene is a lysosomal enzymethat cleaves terminal sialic acid residues from substrates such asglycoproteins and glycolipids. In the lysosome, this enzyme is partof a heterotrimeric complex together with beta-galactosidase andcathepsin A (the latter is also referred to as 'protectiveprotein'). Mutations in this gene can lead to sialidosis, alysosomal storage disease that can be type 1 (cherry redspot-myoclonus syndrome or normosomatic type), which is late-onset,or type 2 (the dysmorphic type), which occurs at an earlier age |
Immunogen | n/a |
Other Names | [Sialidase-1; Acetylneuraminyl hydrolase; G9 sialidase; Lysosomal sialidase; N-acetyl-alpha-neuraminidase 1; NEU1; NANH] |
Gene, Accession # | [NEU1], Gene ID: 4758, NCBI: NP_000425.1, UniProt: Q99519 |
Catalog # | MBS9205504 |
Price | $165, $370 |
Order / More Info | NEU1 (Center), 188-214 Antibody from MYBIOSOURCE INC. |
Product Specific References | Caciotti, A., et al. J. Neurol. 256(11):1911-1915(2009) Bonten, E.J., et al. J. Biol. Chem. 284(41):28430-28441(2009) Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) : Wang, J., et al. J. Neurochem. 111(2):547-554(2009) Lai, S.C., et al. Eur. J. Neurol. 16(8):912-919(2009) |