NEU1 (Center), 188-214 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNEU1 (Center), 188-214
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: bovine)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis NEU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-214 amino acids from the Central region of human NEU1. The protein encoded by this gene is a lysosomal enzymethat cleaves terminal sialic acid residues from substrates such asglycoproteins and glycolipids. In the lysosome, this enzyme is partof a heterotrimeric complex together with beta-galactosidase andcathepsin A (the latter is also referred to as 'protectiveprotein'). Mutations in this gene can lead to sialidosis, alysosomal storage disease that can be type 1 (cherry redspot-myoclonus syndrome or normosomatic type), which is late-onset,or type 2 (the dysmorphic type), which occurs at an earlier age
Immunogenn/a
Other Names[Sialidase-1; Acetylneuraminyl hydrolase; G9 sialidase; Lysosomal sialidase; N-acetyl-alpha-neuraminidase 1; NEU1; NANH]
Gene, Accession #[NEU1], Gene ID: 4758, NCBI: NP_000425.1, UniProt: Q99519
Catalog #MBS9205504
Price$165, $370
Order / More InfoNEU1 (Center), 188-214 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesCaciotti, A., et al. J. Neurol. 256(11):1911-1915(2009) Bonten, E.J., et al. J. Biol. Chem. 284(41):28430-28441(2009) Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) : Wang, J., et al. J. Neurochem. 111(2):547-554(2009) Lai, S.C., et al. Eur. J. Neurol. 16(8):912-919(2009)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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