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Antigenic Specificity | Human CD14 |
Clone | [4AWUCD14] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 4AWUCD14 reacts with CD14, a 53-55 kDa molecule. CD14 is a human high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granulocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regulate cell surface molecules including adhesion molecules.This clone is cross reactive with non-human primate. |
Immunogen | n/a |
Other Names | [CD14; Monocyte differentiation antigen CD14; monocyte differentiation antigen CD14; CD14 molecule; Myeloid cell-specific leucine-rich glycoprotein; CD_antigen: CD14] |
Gene, Accession # | [CD14], Gene ID: 281048, NCBI: BAA21517.1 |
Catalog # | MBS8500489 |
Price | $215, $280 |
Order / More Info | Human CD14 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Knapp, W et al., eds. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York. 2. Makgoba, MW et al., (1988) Nature 331: 86-88. 3. Boyd. AW et al., (1989) Blood 73: 1896-1903. |