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Antigenic Specificity | DUSP7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 0.72mg/mL |
Applications | Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differenti |
Immunogen | Immunogen: Fusion protein of human DUSP7 |
Other Names | [Dual specificity phosphatase 7; Dual specificity protein phosphatase 7; Dual specificity protein phosphatase PYST2; DUS7; Dusp7,Jnk Stimulatory Phosphatase 1,JSP1; MAP kinase phosphatase X; MKPX; PYST2] |
Gene, Accession # | [DUSP7], Gene ID: 1849, NCBI: NP_001938.2, UniProt: Q16829 |
Catalog # | MBS2560865 |
Price | $110, $150, $225 |
Order / More Info | DUSP7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |