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Antigenic Specificity | M TLR5 (N-term), 71-102 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse TLR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-102 amino acids from the N-terminal region of mouse TLR5. TLR5, a Type I membrane protein belonging to the Toll-like receptor family, participates in the innate immune response to microbial agents. It also plays a role in mediating detection of bacterial flagellins. TLR5 acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein binds to TIRAP and MyD88 via their respective TIR domains TLR5 is highly expressed in liver, and is detected in lung and at very low levels in most other tissues. The TLR5 gene lies in a locus that is associated with susceptibility to Salmonel |
Immunogen | n/a |
Other Names | [Toll-like receptor 5; Tlr5] |
Gene, Accession # | [Tlr5], Gene ID: 53791, NCBI: NP_058624.2, UniProt: Q9JLF7 |
Catalog # | MBS9213668 |
Price | $165, $370 |
Order / More Info | M TLR5 (N-term), 71-102 Antibody from MYBIOSOURCE INC. |
Product Specific References | Sebastiani, G., et al., Genomics 64(3):230-240 (2000). |