NBN Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNBN
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionNBN, also named as NBS, NBS1 and P95, is a component of the MRE11/RAD50/NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. NBN also functions in telomere length maintenance by generating the 3' o
ImmunogenImmunogen: A synthetic peptide of human NBN Calculated Molecular Weight: 85kDa
Other Names[p95; NBS1: AT-V1; AT-V2; ATV; FLJ10155; MGC87362; NBS; NBS1; P95], [NBN; NBN; ATV; NBS; P95; NBS1; AT-V1; AT-V2; NBS; NBS1; P95]
Gene, Accession #[NBN], Gene ID: 4683, NCBI: O60934.1, UniProt: O60934
Catalog #MBS126046
Price$200, $275, $430
Order / More InfoNBN Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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