IFN-alpha, Mouse Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | IFN-alpha, Mouse |
| Clone | F18 |
| Host Species | Rat |
| Reactive Species | mouse, human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The monoclonal antibody F18 recognizes and neutralizes both natural and recombinant mouse alpha Interferon (IFN-alpha). IFN-alpha is a cytokine that belongs to the type I interferons (IFN-I). IFN-alpha is secreted by many cell types including lymphocytes (NK cells, B-cells and T-cells), macrophages, fibroblasts, endothelial cells, osteoblasts, microglia and others. Interferons stimulate both macrophages and NK cells to elicit an anti-viral response, and are also active against tumors. Although all cells can produce IFN-I, plasmacytoid dendritic cells (pDCs) produce 1,000-fold higher levels than other cell types, and are responsible for systemic IFN-I responses to many viruses. They are coined as the natural IFN-producing cells. However, und |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [IFN-alpha] |
| Catalog # | MBS584340 |
| Price | $420 |
| Order / More Info | IFN-alpha, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Dalod, M et al; Interferon ;/β and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo. J Exp Med 2002, 195: 517 2. Diebold, S et al; Viral infection switches nonplasmacytoid dendritic cells into high interferon producers. Nature 2003, 424: 324 3. Joshi, V et al; A role for Stat1 in the regulation of lipopolysaccharide-induced Interleukin-1beta expression. J Interferon Cytokine Res 2006, 26: 739. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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