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Antigenic Specificity | RGS7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RGS7 antibody detects endogenous levels of total RGS7. Function: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509). May play a role in synaptic vesicle exocytosis (PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:15897264).Subunit Structure: Interacts with PKD1; this prevents rapid proteasomal degradation (PubMed:10339594). Interacts with GNB5 (PubMed:1 |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasmic |
Other Names | [OTTHUMP00000037994; Regulator of G protein signalling 7; Regulator of G-protein signaling 7; Regulator of G-protein signaling RGS7; Regulator of G-protein signalling 7] |
Gene, Accession # | [RGS7], Gene ID: 6000, NCBI: NP_001269702.1, UniProt: P49802 |
Catalog # | MBS9605872 |
Price | $240, $280 |
Order / More Info | RGS7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |