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Antigenic Specificity | CISH - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CISH |
Other Names | [cytokine-inducible SH2-containing protein isoform 1; Cytokine-inducible SH2-containing protein; cytokine-inducible SH2-containing protein; cytokine inducible SH2 containing protein; CIS-1; Protein G18; Suppressor of cytokine signaling; SOCS] |
Gene, Accession # | [CISH], Gene ID: 1154, NCBI: NP_037456.5, UniProt: Q9NSE2 |
Catalog # | MBS3221517 |
Price | $335 |
Order / More Info | CISH - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |