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Antigenic Specificity | CTSB - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor i |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CTSB |
Other Names | [cathepsin B isoform 1 preproprotein; Cathepsin B; cathepsin B; cathepsin B; APP secretase; APPS; Cathepsin B1Cleaved into the following 2 chains:Cathepsin B light chain; Cathepsin B heavy chain] |
Gene, Accession # | [CTSB], Gene ID: 1508, NCBI: NP_001899.1, UniProt: P07858 |
Catalog # | MBS3221533 |
Price | $335 |
Order / More Info | CTSB - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |