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Antigenic Specificity | Human PLATELET FACTOR-4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml after reconstitution |
Applications | ELISA (EIA), Functional Assays (FN), Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human Platelet Factor-4 antibody specifically recognizes platelet factor-4 (PF-4), otherwise known as CXCL4, a member of the intercrine alpha (chemokine CXC) family, released from the alpha granules of activated platelets, during platelet aggregation. PF-4 binds with high affinity to heparin, counteracting its' anticoagulant effect, thereby promoting blood coagulation, and implicating PF-4 in wound repair. PF-4 acts as a chemotactic factor for neutrophils, monocytes and fibroblasts, and binds wih CXCR3B, a splice variant of the chemokine receptor CXCR3. |
Immunogen | Immunogen: Recombinant human PF-4 Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to human PF-4 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [platelet factor 4; Platelet factor 4; platelet factor 4; C-X-C motif chemokine 4; chemokine (C-X-C motif) ligand 4; iroplact; oncostatin-A; platelet factor 4; C-X-C motif chemokine 4; Iroplact; Oncostatin-APlatelet factor 4, short form], [PF4; PF4; PF-4; CXCL4; SCYB4; CXCL4; SCYB4; PF-4] |
Gene, Accession # | Gene ID: 5196, NCBI: NP_002610.1, UniProt: P02776 |
Catalog # | MBS223824 |
Price | $550 |
Order / More Info | Human PLATELET FACTOR-4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |