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Antigenic Specificity | Human TRAIL |
Clone | [SB91a] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Reacts with Human TRAIL. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family of cytokines. This type II transmembrane protein is expressed by several cytotoxic immune cells, including natural killer cells and activated T cells, and is selective for tumorigenic and virally infected cells2,3. TRAIL can bind to DR4 and DR5 receptors on target cells which facilitates recruitment of numerous signaling proteins to form a death-inducing signaling complex. This signaling complex is then believed to propagate the apoptotic signal through the recruitment and activation of Caspase-84,5. Numerous studies have identified TRAIL as a potent apoptotic factor in a variety of human cancer cell lines, but this cytokin |
Immunogen | Immunogen: Full Length Recombinant Human TRAIL. Characterization: To ensure acceptable performance, each batch of product is tested by ELISA to conform to characteristics of a standard reference reagent. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS670180 |
Price | $360 |
Order / More Info | Human TRAIL Antibody from MYBIOSOURCE INC. |
Product Specific References | 1) Zamai, L. et al. (1998). J. Exp. Med. 188:2375-80.3) Jin, Z. and El-Deiry, W.S. (2006). Mol. Cell. Biol. 26:8136-48.4) Thorburn, A. (2004). Cell. Sign. 16:139-44.5) Micheau, O. and Tschopp, J. (2003). Cell. 114:181-90.6) Nagane, M. et al. (2001). Apop. 6:191-7. |