Human TRAIL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman TRAIL
Clone[SB91a]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b
Formatunconjugated
Size0.5 mg
Concentrationn/a
ApplicationsELISA
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DescriptionReacts with Human TRAIL. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family of cytokines. This type II transmembrane protein is expressed by several cytotoxic immune cells, including natural killer cells and activated T cells, and is selective for tumorigenic and virally infected cells2,3. TRAIL can bind to DR4 and DR5 receptors on target cells which facilitates recruitment of numerous signaling proteins to form a death-inducing signaling complex. This signaling complex is then believed to propagate the apoptotic signal through the recruitment and activation of Caspase-84,5. Numerous studies have identified TRAIL as a potent apoptotic factor in a variety of human cancer cell lines, but this cytokin
ImmunogenImmunogen: Full Length Recombinant Human TRAIL. Characterization: To ensure acceptable performance, each batch of product is tested by ELISA to conform to characteristics of a standard reference reagent.
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS670180
Price$360
Order / More InfoHuman TRAIL Antibody from MYBIOSOURCE INC.
Product Specific References1) Zamai, L. et al. (1998). J. Exp. Med. 188:2375-80.3) Jin, Z. and El-Deiry, W.S. (2006). Mol. Cell. Biol. 26:8136-48.4) Thorburn, A. (2004). Cell. Sign. 16:139-44.5) Micheau, O. and Tschopp, J. (2003). Cell. 114:181-90.6) Nagane, M. et al. (2001). Apop. 6:191-7.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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