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Antigenic Specificity | ASF1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ASF1B antibody detects endogenous levels of total ASF1B. Function: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis.Subunit Structure: Interacts with histone H3 (including both histone H3.1 and H3.3) and histone H4. Interacts with the CHAF1A, CHAF1B and RBBP4 subunits of the CAF-1 complex. Interacts with HAT1, NASP, TAF1, TLK1 and TLK2. Interacts with CDAN1. Found in a cytosolic complex with CDAN1, ASF1A, I |
Immunogen | Immunogen: A synthesized peptide derived from human ASF1B Subcellular Location: Nucleus. Tissue Specificity: Highly expressed in testis and at lower levels in colon, small intestine and thymus. Predicted Cross Reactivity: Bovine, Sheep, Rabbit, Xenopus Similarity: Bovine (89%), Sheep (89%), Rabbit (89%), Xenopus (89%) |
Other Names | [silencing function 1B; silencing function 1B histone chaperone; silencing function protein 1 homolog B; ASF1 silencing function 1 homolog B (S. cerevisiae); ASF1 silencing function 1 homolog B; ASF1B; ASF1B_HUMAN; CCG1 interacting factor A II; CCG1-interacting factor A-II; CIA-II; hAsf1; hAsf1b; hCIA-II; Histone chaperone ASF1B] |
Gene, Accession # | [ASF1B], Gene ID: 55723, NCBI: NP_060624.1, UniProt: Q9NVP2 |
Catalog # | MBS9602065 |
Price | $240, $280 |
Order / More Info | ASF1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |