PAK2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPAK2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionPAK2 Antibody: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6, and are not activated by Cdc42/Rac binding. Of the six PAK proteins, only PAK2 is ubiquitously expressed and cleaved by caspase-3. This cleavage removes the amino-terminal regulatory domain and genera
ImmunogenImmunogen: PAK2 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human PAK2. Buffer: PAK2 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[PAK2; PAK65; PAKgammaGamma-PAK; PAK-2; p21 protein (Cdc42/Rac)-activated kinase 2], [PAK2; PAK2; PAK65; PAKgamma; PAK-2; p27; p34]
Gene, Accession #[PAK2], Gene ID: 5062, NCBI: NP_002568, UniProt: Q13177
Catalog #MBS151095
Price$375
Order / More InfoPAK2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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