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Antigenic Specificity | CD6 |
Clone | [C6/372 + 3F7B5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular -scavenger receptor cysteine-rich- (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease. |
Immunogen | Immunogen: Human recombinant CD6 protein (C6/372); Human rheumatoid synovial T cell line ST-1 (3F7B5) |
Other Names | [T12; TP120], [CD6; CD6; TP120] |
Gene, Accession # | [CD6], Gene ID: 923, NCBI: NP_001241679.1, UniProt: P30203 |
Catalog # | MBS438051 |
Price | $190, $340, $340 |
Order / More Info | CD6 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bazil, V et. al. 1989. Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102. Folia. Biol. 35:289-297 |