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Antigenic Specificity | Human Tyrosine-protein phosphatase non-receptor type 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET. |
Immunogen | Immunogen: Recombinant human Tyrosine-protein phosphatase non-receptor type 1 protein (281-435aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1719 / sc-1718 / sc-14021 |
Other Names | [Protein-tyrosine phosphatase 1B; PTP-1B; PTPN1; PTP1B], [PTPN1; PTPN1; PTP1B; PTP1B; PTP-1B] |
Gene, Accession # | [PTPN1], Gene ID: 5770, NCBI: NP_001265547.1, UniProt: P18031 |
Catalog # | MBS968910 |
Price | $120, $160 |
Order / More Info | Human Tyrosine-protein phosphatase non-receptor type 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |