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Antigenic Specificity | DCLK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DCLK2 antibody detects endogenous levels of total DCLK2. Function: Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity).Subunit Structure: Binds to and stabilizes microtubules. Interacts with MAPK8IP1/JIP-1, MAPK8IP2/JIP-2, MAPK9/JNK2, PPP1R9B/NEURABIN-2 and actin.Post-translational Modifications: Autophosphorylated.Similarity: The doublecortin domains are involved in the colocalization with microtubules. Belongs to the protein kinase superfam |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm > Cytoskeleton. Colocalizes with microtubules. Tissue Specificity: Expressed in the brain, heart and eyes. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%) |
Other Names | [CaMK-like CREB regulatory kinase 2; CL2; CLICK-II; CLICK2; DCAMK L2; DCAMKL 2; DCDC 3; DCDC 3B; DCDC3; DCDC3B; DCK 2; DCK2; DCLK 2; Dclk2; DCLK2_HUMAN; DKFZp761I032; Doublecortin and CaM kinase like 2; Doublecortin domain-containing protein 3B; Doublecortin like and CAM kinase like 2; Doublecortin like kinase 2; Doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2; MGC45428; Serine/threonine protein kinase DCLK2; Serine/threonine-protein kinase DCLK2] |
Gene, Accession # | [DCLK2], Gene ID: 166614, NCBI: NP_001035350.2, UniProt: Q8N568 |
Catalog # | MBS9604810 |
Price | $240, $280 |
Order / More Info | DCLK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |