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Antigenic Specificity | Human Guanine nucleotide-binding protein-like 3-like |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. |
Immunogen | Immunogen: Recombinant human Guanine nucleotide-binding protein-like 3-like protein(1-582AA) |
Other Names | [GNL3L], [GNL3L; GNL3L] |
Gene, Accession # | [GNL3L], Gene ID: 54552, NCBI: NP_001171748.1, UniProt: Q9NVN8 |
Catalog # | MBS1495160 |
Price | $160, $235 |
Order / More Info | Human Guanine nucleotide-binding protein-like 3-like Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |