Human Guanine nucleotide-binding protein-like 3-like Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Guanine nucleotide-binding protein-like 3-like
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatbiotin conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionStabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
ImmunogenImmunogen: Recombinant human Guanine nucleotide-binding protein-like 3-like protein(1-582AA)
Other Names[GNL3L], [GNL3L; GNL3L]
Gene, Accession #[GNL3L], Gene ID: 54552, NCBI: NP_001171748.1, UniProt: Q9NVN8
Catalog #MBS1495160
Price$160, $235
Order / More InfoHuman Guanine nucleotide-binding protein-like 3-like Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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