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Antigenic Specificity | PGC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.7 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total PGC protein. This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Full length fusion protein |
Other Names | [PEPC; PGII] |
Gene, Accession # | [PGC], Gene ID: 5225, NCBI: NP_001159896.1, UniProt: P20142 |
Catalog # | MBS9406235 |
Price | $255 |
Order / More Info | PGC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |