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Antigenic Specificity | DAPK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylates TPM1, enhancing stress fiber formation in endothelial cells. Phosphorylates STX1A and significantly decreases its binding to STXBP1. Phosphorylates PRKD1 and regulates JNK signaling by binding and activating PRKD1 u |
Immunogen | Immunogen: Recombinant human Death-associated protein kinase 1 protein (1141-1430aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-8164 / sc-10805 |
Other Names | [DAP kinase 1; DAPK1; DAPK], [DAPK1; DAPK1; DAPK; DAPK; DAP kinase 1] |
Gene, Accession # | [DAPK1], Gene ID: 1612, NCBI: NP_001275658.1, UniProt: P53355 |
Catalog # | MBS1498279 |
Price | $120, $160 |
Order / More Info | DAPK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |