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Antigenic Specificity | EHD1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: EHD1 antibody detects endogenous levels of total EHD1. Function: ATP-and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes (PubMed:24019528). Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes (PubMed:15020713, PubMed:17233914, PubMed:20801876). Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth (By similarity). Plays a role in myoblast fusion (By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing (By s |
Immunogen | Immunogen: A synthesized peptide derived from human EHD1 Subcellular Location: Cell Membrane. Early Endosome Membrane. Recycling Endosome Membrane. Associated with intracellular tubulovesicular structures. Tissue Specificity: Highly expressed in testis. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Xenopus (92%) |
Other Names | [CDABP0131; EH domain containing 1; EH domain-containing protein 1; EHD1; EHD1_HUMAN; FLJ42622; FLJ44618; H PAST; hPAST1; PAST; PAST homolog 1; PAST1; Testilin] |
Gene, Accession # | [EHD1], Gene ID: 10938, NCBI: NP_001269373.1, UniProt: Q9H4M9 |
Catalog # | MBS9608460 |
Price | $240, $280 |
Order / More Info | EHD1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |