TAB3 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | TAB3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TAB3 antibody is human specific. TAB3 antibody is predicted not to cross-react with other TAB proteins. TAB3 Antibody: TAB3 functions in the NF-kappaB signal transduction pathway. It and the similar and functionally redundant protein TAB2, form a ternary complex with the protein kinase TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1; upon induction of autophagy, these proteins dissociate from Beclin-1 and bind TAK1. Overe |
| Immunogen | Immunogen: TAB3 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human TAB3. Buffer: TAB3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [TAB3; NAP1; MAP3K7IP3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3; Mitogen-activated protein kinase kinase kinase 7-interacting protein 3; TAB-3; TGF-beta activated kinase 1/MAP3K7 binding protein 3], [TAB3; TAB3; NAP1; MAP3K7IP3; MAP3K7IP3; TAB-3] |
| Gene, Accession # | [TAB3], Gene ID: 257397, NCBI: NP_690000, UniProt: Q8N5C8 |
| Catalog # | MBS150688 |
| Price | $375 |
| Order / More Info | TAB3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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