CD180, Mouse Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD180, Mouse |
| Clone | RP/14 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), FS |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: Radioprotective 105 (RP105, CD180) is a type 1 transmembrane protein of 105 kDa with extracellular leucine-rich repeats (LLRs) and a short cytoplasmic tail. RP105, assigned as CD180, is similar to Drosophila Toll in the extracellular LLRs. Radioprotective 105 (RP105, CD180) expression is largely restricted to immune cells including CD19 B cells and macrophages. Histological studies showed that RP105 is expressed mainly on mature B cells in mantle zones. Antibody-mediated (RP/14) cross-linking of RP105 induces resistance against irradiation-induced apoptosis, B-cell proliferation, and up-regulation of a costimulatory molecule B7.2, revealing RP105 as a potent regulator of B-cell activation. RP105 (CD180) has an important |
| Immunogen | n/a |
| Other Names | [RP105, Ly78], [CD180; CD180; LY64; Ly78; RP105; LY64; RP105] |
| Gene, Accession # | [CD180], Gene ID: 4064, NCBI: NP_005573.2 |
| Catalog # | MBS584021 |
| Price | $470 |
| Order / More Info | CD180, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Miyake, K et al; Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. J Immunol 1998, 161: 1348 2. Nagai, Y et al; Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide. Blood 2002, 99: 1699 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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