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Antigenic Specificity | ER-beta1 (Estrogen Receptor beta-1) |
Clone | [ESR2/686] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone a |
Immunogen | Immunogen: C-terminus fragment of recombinant human estrogen receptor beta protein |
Other Names | [Erb, ESR BETA, ESR2, ESRB, ESTRB, estrogen nuclear receptor beta variant a, estrogen nuclear receptor beta variant b, estrogen receptor 2 (ER beta), estrogen receptor beta 4], [ESR2; ESR2; Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA; ESTRB; NR3A2; ER-beta] |
Gene, Accession # | [ESR2], Gene ID: 2100, NCBI: NP_001035365.1, UniProt: Q92731 |
Catalog # | MBS439629 |
Price | $190, $340, $340 |
Order / More Info | ER-beta1 (Estrogen Receptor beta-1) Antibody from MYBIOSOURCE INC. |
Product Specific References | Skliris GP et. al. J Pathol 2002;197:155-62. |