Human Interleukin-12 subunit beta Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Interleukin-12 subunit beta
Clone[PAT1D6AT]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1 k
FormatProtein G purified
Size0.005 mg, 0.02 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionIntroduction: IL12B is a subunit of interleukin 12 which is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40kDa cytokine receptor like subunit encoded by the IL12B gene, and a 35kDa subunit encoded by IL12A. The IL12B cytokine is expressed by activated macrophages which serve as an important inducer of Th1 cells development. The IL12B cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of the IL12B gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting
ImmunogenImmunogen: Anti-human IL12B mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human IL12B amino acids 23-328 purified from E Coli.
Other Names[IL12B; Interleukin-12 subunit beta, Mouse Human; Interleukin-12 subunit beta; IL-12 subunit p40; Cytotoxic lymphocyte maturation factor 40 kDa subunit; NK cell stimulatory factor chain 2; IL-12B; CLMF p40; NKSF2; IL12B; CLMF; CLMF2; IL-12B], [IL12B; IL12B; CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B; NKSF2; IL-12B; CLMF p40; NKSF2]
Gene, Accession #[IL12B], Gene ID: 3593, NCBI: NP_002178.2
Catalog #MBS140276
Price$140, $205, $505
Order / More InfoHuman Interleukin-12 subunit beta Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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