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Antigenic Specificity | Synaptophysin |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | mouse, rat. predicted to work with: human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Synaptophysin(SYP) detection. Tested with WB in Human;Mouse;Rat. Background: SYP(Synaptophysin) is located on the short arm of X chromosome (Xp11.23-p11.22). The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kDa. It is present inneuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses. Also, the protein binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular comp |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Synaptophysin(1-26aa MLLLADMDVVNQLVAGGQFRVVKEPL), identical to the related mouse and rat sequences. Ig Type: Rabbit IgG |
Other Names | [Synaptophysin; Major synaptic vesicle protein P38; MRXSYP; Syn p38; Synaptophysin; SYP; SYPH; SYPH_HUMAN; SypI; synaptophysin], [SYP; SYP; MRX96; MRXSYP] |
Gene, Accession # | Gene ID: 6855, NCBI: NP_003170.1, UniProt: P08247 |
Catalog # | MBS178239 |
Price | $280 |
Order / More Info | Synaptophysin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Calhoun ME, Jucker M, Martin LJ, Thinakaran G, Price DL, Mouton PR (December 1996). Comparative evaluation of synaptophysin-based methods for quantification of synapses. J. Neurocytol.25 (12): 821-8. |