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Antigenic Specificity | Human Haptoglobin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equ |
Immunogen | Immunogen: Recombinant human Haptoglobin protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-68667 / sc-134466 / sc-134464 |
Other Names | [Zonulin], [HP; HP; BP; HPA1S; HP2ALPHA2] |
Gene, Accession # | [HP], Gene ID: 3240, NCBI: NP_001119574.1, UniProt: P00738 |
Catalog # | MBS1489352 |
Price | $160, $235 |
Order / More Info | Human Haptoglobin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |