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Antigenic Specificity | Mouse E-Selectin |
Clone | [9J12] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) - Paraffin, Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | E-Selectin (Endothelial Leukocyte Adhesion Molecule1, ELAM1, CD62E), a member of the Selectin family, is a 107-115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL 1beta and TNFalpha, and demonstrates peak expression at 4 hours, and decay at 24 hours, in response to activation. E-Selectin ligands, expressed on neutrophils, monocytes, and a subset of memory T cells, are sialylated, fucosylated molecules which bind to the lectin domain of E-Selectin. Immunocytochemical techniques have demonstrated the expression of E-Selectin on healthy and diseased tissue. The human and mouse E-Selectin proteins share 81% amino acid similarity. E-Selectin mediates the attachment of flowing leukocytes |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with cytokine stimulated-mouse endothelial membrane protein). IgG2 fraction of the culture supernatant was purified by Protein G affinity chromatography. |
Other Names | [Sele; Elam; CD62E; E-selectin], [Sele; Sele; Elam; CD62E; E-selectin; Elam-1; ELAM-1; LECAM2] |
Gene, Accession # | Gene ID: 20339, NCBI: NP_035475.1, UniProt: Q00690 |
Catalog # | MBS690956 |
Price | $490 |
Order / More Info | Mouse E-Selectin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |