Mouse E-Selectin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse E-Selectin
Clone[9J12]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) - Paraffin, Flow Cytometry (FC/FACS)
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DescriptionE-Selectin (Endothelial Leukocyte Adhesion Molecule1, ELAM1, CD62E), a member of the Selectin family, is a 107-115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL 1beta and TNFalpha, and demonstrates peak expression at 4 hours, and decay at 24 hours, in response to activation. E-Selectin ligands, expressed on neutrophils, monocytes, and a subset of memory T cells, are sialylated, fucosylated molecules which bind to the lectin domain of E-Selectin. Immunocytochemical techniques have demonstrated the expression of E-Selectin on healthy and diseased tissue. The human and mouse E-Selectin proteins share 81% amino acid similarity. E-Selectin mediates the attachment of flowing leukocytes
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with cytokine stimulated-mouse endothelial membrane protein). IgG2 fraction of the culture supernatant was purified by Protein G affinity chromatography.
Other Names[Sele; Elam; CD62E; E-selectin], [Sele; Sele; Elam; CD62E; E-selectin; Elam-1; ELAM-1; LECAM2]
Gene, Accession #Gene ID: 20339, NCBI: NP_035475.1, UniProt: Q00690
Catalog #MBS690956
Price$490
Order / More InfoMouse E-Selectin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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