Mib1/Mindbomb Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Mib1/Mindbomb |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Direct ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Mib1 Mindbomb detection. Tested with WB, Direct ELISA in Human; Mouse; Rat.Background: E3 ubiquitin-protein ligase MIB1 is an enzyme that in humans is encoded by the MIB1 gene. It is mapped to 18q11.2. This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). |
| Immunogen | Immunogen: E Coli-derived human Mib1 Mindbomb recombinant protein (Position: H465-E732). |
| Other Names | [E3 ubiquitin-protein ligase MIB1; DAPK-interacting protein 1; DIP-1; Mind bomb homolog 1; RING-type E3 ubiquitin transferase MIB1; Zinc finger ZZ type with ankyrin repeat domain protein 2; MIB1; DIP1; KIAA1323; ZZANK2; Mindbomb E3 ubiquitin protein ligase 1] |
| Gene, Accession # | [MIB1], Gene ID: 57534, NCBI: NP_065825.1, UniProt: Q86YT6 |
| Catalog # | MBS1751343 |
| Price | $280 |
| Order / More Info | Mib1/Mindbomb Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Barsi, J. C., Rajendra, R., Wu, J. I., Artzt, K. Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling. Mech. Dev. 122: 1106-1117, 2005. 2. Henshall, D. C., Schindler, C. K., So, N. K., Lan, J.-Q., Meller, R., Simon, R. P.Death-associated protein kinase expression in human temporal lobe epilepsy. Ann. Neurol. 55: 485-494, 2004. 3. Jin, Y., Blue, E. K., Dixon, S., Shao, Z., Gallagher, P. J. A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK. J. Biol. Chem. 277: 46980-46986, 2002. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
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