Mouse Cbx7 (C-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse Cbx7 (C-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis Mouse Cbx7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 144-178 amino acids from the C-terminal region of human Mouse Cbx7. Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to histone H3 trimethylated 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). May possibly also bind trimethylated
Immunogenn/a
Other Names[Chromobox protein homolog 7; Cbx7; D15Ertd417e]
Gene, Accession #[Cbx7], Gene ID: 52609, NCBI: NP_659060.1, UniProt: Q8VDS3
Catalog #MBS9212668
Price$165, $370
Order / More InfoMouse Cbx7 (C-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGil J.,et al.Nat. Cell Biol. 6:67-72(2004). Bernstein E.,et al.Mol. Cell. Biol. 26:2560-2569(2006). Yap K.L.,et al.Mol. Cell 38:662-674(2010).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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