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Antigenic Specificity | CNOT8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total CNOT8 polyclonal antibody. Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is requi |
Immunogen | Immunogen: Recombinant Human CCR4-NOT transcription complex subunit 8 protein (1-292aa) |
Other Names | [CAF1-like protein; CALIFp; CAF2; CCR4-associated factor 8; Caf1b; CNOT8; CALIF; POP2] |
Gene, Accession # | [CNOT8], Gene ID: 9337, NCBI: NP_001288002.1, UniProt: Q9UFF9 |
Catalog # | MBS9416096 |
Price | $320 |
Order / More Info | CNOT8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |