CNOT8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCNOT8
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous level of total CNOT8 polyclonal antibody. Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is requi
ImmunogenImmunogen: Recombinant Human CCR4-NOT transcription complex subunit 8 protein (1-292aa)
Other Names[CAF1-like protein; CALIFp; CAF2; CCR4-associated factor 8; Caf1b; CNOT8; CALIF; POP2]
Gene, Accession #[CNOT8], Gene ID: 9337, NCBI: NP_001288002.1, UniProt: Q9UFF9
Catalog #MBS9416096
Price$320
Order / More InfoCNOT8 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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