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Antigenic Specificity | SMAC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SMAC is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/caspase-9 pathway. Smac/DIABLO binds to IAPs and neutralizes the inhibitory effect of IAPs. Analysis of the structural basis of Smac/DIABLO has revealed that the N-terminal amino acids are required for Smac/DIABLO to bind to IAPs and activation of caspases. |
Immunogen | Immunogen: SMAC antibody was raised in Rabbit using synthetic peptide surrounding amino acid 220 of mouse Smac/DIABLO as the immunogen. |
Other Names | [Rabbit SMAC; SMAC; SMAC; DIABLO-S; FLJ10537; SMAC3; FLJ25049; DIABLO; 0610041G12Rik] |
Gene, Accession # | [SMAC], Gene ID: 56616 |
Catalog # | MBS5311255 |
Price | $430 |
Order / More Info | SMAC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |