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Antigenic Specificity | DRD2 (C-term), 307-336 |
Clone | [629CT62.2.2] |
Host Species | Mouse |
Reactive Species | mouse, rat |
Isotype | IgG2a |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DRD2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the C-terminal region of human DRD2. This gene encodes the D2 subtype of the dopamine receptor.This G-protein coupled receptor inhibits adenylyl cyclase activity.A missense mutation in this gene causes myoclonus dystonia; othermutations have been associated with schizophrenia. Alternativesplicing of this gene results in two transcript variants encodingdifferent isoforms. A third variant has been described, but it hasnot been determined whether this form is normal or due to aberrantsplicing. |
Immunogen | n/a |
Other Names | [D(2) dopamine receptor; Dopamine D2 receptor; DRD2] |
Gene, Accession # | [DRD2], Gene ID: 1813, NCBI: NP_000786.1, UniProt: P14416 |
Catalog # | MBS9200336 |
Price | $370 |
Order / More Info | DRD2 (C-term), 307-336 Antibody from MYBIOSOURCE INC. |
Product Specific References | Verma, V., et al. J. Biol. Chem. 285(45):35092-35103(2010) Borroto-Escuela, D.O., et al. Biochem. Biophys. Res. Commun. 401(4):605-610(2010) Stelzel, C., et al. J. Neurosci. 30(42):14205-14212(2010) Huang, H.Y., et al. J. Formos. Med. Assoc. 109(10):736-739(2010) Itokawa, M., et al. J. Pharmacol. Sci. 114(1):1-5(2010) |