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Antigenic Specificity | EHMT2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total EHMT2 protein. G9a, also known as Euchromatic histone-lysine N-methyltransferase 2 (EHMT2), is a member of a family of histone lysine methyltransferases, each of which contains a conserved catalytic SET domain originally identified in Drosophila Su3-9, Enhancer of zeste, and Trithorax proteins (1). Recombinant G9a can mono-, di- and tri-methylate histone H3 on Lys9 and Lys27 in vitro (1,2). However, in vivo G9a forms a complex with GLP, a G9a-related histone methyltransferase, and together these proteins function as the major euchromatic histone H3 Lys9 mono- and di-methyltransferases, creating transcriptionally repressive marks that facilitate gene silencing (3,4). G9a methylates itself on Lys |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human EHMT2. |
Other Names | [EHMT2; BAT8; C6orf30; DKFZp686H08213; FLJ35547] |
Gene, Accession # | [EHMT2], Gene ID: 10919, NCBI: NP_001276342.1, UniProt: Q96KQ7 |
Catalog # | MBS9404117 |
Price | $255 |
Order / More Info | EHMT2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |