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Antigenic Specificity | Cbx5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Chromobox homolog 5 (Cbx5), lso known as HP1 is an evolutionarily conserved non-histone chromosomal protein involved in many biological progresses, such as heterochromatin formation, transcriptional regulation, DNA recombination and damage repair, RNA interference, kinetochore protein assembly, chromatin condensation and sister chromatid cohesion regulation. It binds lysine 9-methylated histone H3 (H3K9me), a hallmark of heterochromatin, and plays a crucial role in forming higher-order chromatin structures.Cbx5 has a conserved N-terminal chromo domain (CD), 3 a non-conserved hinge region, and a C-terminal chromo shadow domain. It localizes to centromeres in interphase through its CD domain, whereas mitotic centromeric localization depends o |
Immunogen | Immunogen Information: Full length recombinant Cbx5 protein was used as the immunogen for this antibody. |
Other Names | [CBX5; HP1A; Antigen p25; HP1 alpha; Heterochromatin protein 1 homolog alpha; to Cbx5; Cbx5; Cbx5], [CBX5; CBX5; HP1; HP1A; HEL25; HP1A; HP1 alpha] |
Gene, Accession # | [CBX5], Gene ID: 23468, NCBI: P45973.1, UniProt: P45973 |
Catalog # | MBS668582 |
Price | $270 |
Order / More Info | Cbx5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |