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Antigenic Specificity | ALOX5 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ALOX5 Antibody detects endogenous levels of total ALOX5. 5-Lipoxygenase (5-LO, ALOX5) is an important catalytic enzyme responsible for the biosynthesis of leukotriene LTA4 from arachidonic acid (1, 2). Leukotriene synthesis also requires 5-lipoxygenase-activating protein (FLAP, ALOX5AP), a nuclear membrane-bound protein that binds arachidonic acid and is thought to activate 5-LO. A number of related leukotrienes (i.e. B4, C4, D4) are derived from LTA4 and together these lipid mediators function in immune reaction regulation. 5-LO is primarily expressed in polymorphonuclear leukocytes, peripheral blood monocytes, macrophages, and mast cells (1, 3). Overexpression of 5-LO protein is seen in certain cancer cells and is associated |
Immunogen | Immunogen: Recombinant protein of human ALOX5 |
Other Names | [5-LO; 5-LOX; 5LPG; LOG5; MGC163204] |
Gene, Accession # | [ALOX5], Gene ID: 240, NCBI: NP_000689.1, UniProt: P09917 |
Catalog # | MBS8516351 |
Price | $290 |
Order / More Info | ALOX5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |