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Antigenic Specificity | PLS3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PLS3 protein. May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human PLS3 protein at amino acid sequence of 180-260 |
Other Names | [Rabbit PLS3; Phospholipid scramblase 3; PL scramblase 3; Ca(2+)-dependent phospholipid scramblase 3] |
Gene, Accession # | [PLS3], Gene ID: 57048, NCBI: NP_001188505.1, UniProt: Q9NRY6 |
Catalog # | MBS9710495 |
Price | $130, $220, $325 |
Order / More Info | PLS3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |