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Antigenic Specificity | CC2D1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses. Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole coh |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CC2D1A (NP 060191.3). |
Other Names | [MRT3; FREUD-1; Freud-1/Aki1] |
Gene, Accession # | [CC2D1A], Gene ID: 54862, NCBI: Q6P1N0.1, UniProt: Q6P1N0 |
Catalog # | MBS8548240 |
Price | $280 |
Order / More Info | CC2D1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |